Rod P. Musselman, Dr. PH

 

EDUCATION

1984
Post-Doctorate
Department of Medicine, University of Illinois Medical Center

1982
Doctor of Public Health
University of Illinois at Chicago,

1973
Master of Public Health
University of Illinois School of Public,

1973
Master of Divinity
Garrett Theological Seminary

1968
Biological Sciences, BA
DePauw University

PROFESSIONAL EXPERIENCE

1997 – Present
President, R P. Musselman Inc.
Environmental and Occupational Health Consultant

1988 – 1997
Corporate Toxicologist
United States Gypsum Company

1984 – 1988
Industry Consultant

PROFESSIONAL AFFILIATIONS

• New York Academy of Sciences

• American College of Toxicology

PUBLICATIONS AND PRESENTATIONS

Musselman R. Urban Soil Remediation with Gypsum and Soluble Phosphates. Presented at the AIHA Chicago Chapter Meeting. March 16, 2010.

Musselman R. Gypsum for Reclaiming Soils. Presented at the Building Materials for Re-Use Association (BMRA) Session 13. DECON09. University of Illinois at Chicago, Chicago, IL, April 29, 2009.

Musselman R. Use of New Scrap Gypsum Wallboard on Urban Soils to Help Immobilize and Remove Lead and Other Toxic Metals, Conserve Soil Moisture, and Reduce Phosphorus Run-off to Surface Waters. Presentation for Water Sustainability Workshop, sponsored by the Institute for Public Health and Water Research, October 23 – 24, 2008, San Diego, CA.

Musselman R. Safety Assessment of Gypsum. Attachment A of Letter from Dr. Charlie Byers , Manager of Product Safety & Industrial Hygiene, USG Corporation to Dr. Scott A. Masten, Director, Office of Chemical Nomination & Selection, NIEHS/NTP, May 10, 2006. Available at http://ntp.niehs.nih.gov/files/USG_Byers_051006_att.pdf.

Musselman R, Miiller W, Estes W, Hadley J, Kamstrup O, Thevenaz P, Hesterberg TH. Biopersistence of crocidolite vs. man-made vitreous fibers (MMVF) in rat lungs after brief exposures. In: Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract. U. Mohr, D.L. Dungworth, J. L. Mauderly, and G. Oberdorster, ed. International Life Sciences Institute/ILSI Press, Washington, DC, 1994:451-454.

McConnell EE, Kamstrup O, Musselman R, Hesterberg TW, Chevalier J, Miiller WC, Thevenaz P. Chronic inhalation study of size-separated rock and slag wool insulation fibers in Fischer 344/N rats. Inhalation Toxicology. Volume 6, Number 6, 1994: 571-614.

Musselman R, Miiller, W, Eastes, W, Hadley, J Kamstrup O, Thevenaz P, Hesterberg TH. Biopersistences of man-made vitreous fibers (MMVF) and crocidolite fibers in rat lungs following short-term exposures. Environmental Health Perspectives. Vol. 102, Supplement 5, October, 1994: 139-143. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567257/?tool=pubmed.

Wong O and Musselman R. An epidemiological and toxicological evaluation of the carcinogenicity of man-made vitreous fiber, with a consideration of coexposures. Journal of Environmental Pathology, Toxicology, and Oncology. 13(3), 1994: 169-180.

Musselman R. Biopersistence of some man-made vitreous fibers and crocidolite asbestos fibers in rodent lungs – Preliminary results. Session IV. Man-Made Vitreous Fibers. The Toxicology Forum. Winter, 1992: 383 – 399.

SYNERGISTIC ACTIVITY

Development and/or refinement of research tools:

Musselman, R., Miiller, W., Eastes, W., Hadley J, Kamstrup O, Thevenaz P, Hesterberg TH. Biopersistences of man-made vitreous fibers (MMVF) and crocidolite fibers in rat lungs following short-term exposures. Environmental Health Perspectives. Vol. 102, Supplement 5, October, 1994: 139-143.

This study refined a protocol and methodology¹ for an experimental animal study measuring the durability (biopersistence) of fibers in rodent lung tissue. The short-term biopersistence study showed that insulation glass wool, rock wool and slag wool fibers do not stay in lung tissue to cause injury. A second biopersistence study reduced the time period of this protocol from nine to six months.² This protocol was codified under Note Q of the European Directive 97/69/EC (5 Dec, 1997) as one of four tests which can be used to show that a classification of a substance as a carcinogen need not apply if it can be shown that the substance fulfills one of the following conditions: (1) a short-term biopersistence test by inhalation showed that fibers longer than 20 micrometers (µm) have a weighted half life less than 10 days (2) a short-term biopersistence test by intratracheal instillation has shown that fibers longer than 20 µm have a weighted half life less than 40 days (3) an appropriate intra-peritoneal test has shown no evidence of excess carcinogenicity, or (4) absence of relevant pathogenicity or neoplastic changes in a suitable long term inhalation test.

¹ Hammad YY. Deposition and elimination of MMF. In: Biological Effects of Mineral Fibers. Copenhagen WHO Conference, 1984: 126 – 142.
² Bernstein DM, Mast R, Anderson R, Hesterberg, TW, Musselman, R, Kamstrup O, Hadley J (1994) An experimental approach to the evaluation of biopersistence of respirable synthetic fibers and minerals. Environmental Health Perspectives, Vol. 102, Supplement 5, pages 15-18.

GRADUATE ADVISORS

Thesis:
The Role of Nitrogen Dioxide in the Biosynthesis of Nitrosamines in Mice Gavaged with Beer. Studies were undertaken to investigate in vitro and in vivo the nitrosation of amines. Results indicated that NO2 gas induces nitrosation of amines present in beer and in animal tissues to nitrosamines.Thesis Advisor: Dr. Samuel S. Epstein, Emeritus Professor, University of Illinois School of Public Health Committee Members: Drs. Bertram W. Carnow, Deceased, Samuel S. Epstein, and Edward Hermann, Emeritus Professor, University of Illinois School of Public Health.

Post – Doctoral:
Sponsor: Ruy V. Lourenço, MD, Executive Head of the Department of Medicine, University of Illinois College of Medicine. Objective of research was to develop unsedated dog and baboon models of mucociliary transport using radioaerosol techniques. The models developed reacted to drugs such as isoproterenol and atropine in the same manner as in humans. These animal models avoided the effects associated with invasive techniques and anesthesia in animal models used to study the effect of maturation, drugs, disease and inhaled pollutants on mucociliary transport. A paper was published from this work: Griffin CL, Musselman, RP, Yeates DB, Raju, TN, Harsbarger RD, Lourenço RV. Hand – Rearing baboons for laboratory investigations. Laboratory Animal Science. 1986, 36(6): 686 – 690.